Santa Praxedes is one of twenty-eight (28) municipalities (along with one city) that comprise the province of Cagayan in the Cagayan Valley. The town is politically subdivided into ten (10) barangays, and is a part of the 2nd Congressional District of Cagayan.

Santa Praxedes is blessed with a wide expanse of fine sand beaches sprawling along its coast. A hilly coastal area bordering the Ilocos Region, it is noted for its hot springs as well as its waterfalls.